Determination of Peroxide Value in Hydroxycamptothecin Freeze-dried Liposome / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-533944
ABSTRACT
OBJECTIVE:
To establish a method for the determination of the peroxide value of hydroxycamptothecin freeze-dried liposome.METHODS:
Colorimetric method with ferric thiocyanate and UV spectrophotometry were adopted for the content determination of peroxide value at detection wavelength of 500 nm.RESULTS:
The linear range of iron was 0.2~4 ?g?mL-1 (r=0.999 0) with an average recovery of 99.2% (RSD=1.2%, n=9). The peroxide value of 3 batches of hydroxycamptothecin freeze-dried liposome was 0.48,0.45,0.43 mmol?kg-1.CONCLUSION:
The method is sensitive and precise for the determination of the peroxide value of liposome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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