Effect of extract of Oratosquilla oratoria on telomerase activity in human nasopharyngeal carcinoma cell line / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
in Chinese
| WPRIM
| ID: wpr-534016
ABSTRACT
AIM:
To study the inhibitory effect and its mechanisms of the extract of Oratosquilla oratoria (EOS) on the activity of telomerase in human nasopharyngeal carcinoma cell line CNE-2Z.METHODS:
MTT assay was used to determine the effect of different doses of EOS on the proliferation of CNE -2Z cells. The activity of telomerase was analyzed by TRAP-ELISA. The mRNA expression of hTERT was determined by RT-PCR,and the protein expression of c-Myc was detected by Western blotting.RESULTS:
EOS inhibited the proliferation of CNE-2Z cells in a dose-dependent manner (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1989
Type:
Article
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