Efficacy Observation of Domestic Recombinant Human Interleukin-11(Ⅰ)in the Treatment of Thrombocytopenia Induced by Radiotherapy and Chemotherapy / 中国药房
China Pharmacy
; (12)2005.
Article
in Zh
| WPRIM
| ID: wpr-534139
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:To observe clinical efficacy and ADR of domestic recombinant human interleukin-11(Ⅰ)(rhIL-11 (Ⅰ))in the treatment of thrombocytopenia in patients with malignant tumor. METHODS:In self-controlled trial,50 malignant tumor patients with thrombocytopenia induced by radiotherapy and chemotherapy were injected with 25 ?g?kg-1?d-1 rhIL-11(Ⅰ) subcutaneously. Drug withdrawal was conducted after consecutive 10 days injection or platelet count being higher than 300?109?L-1. RESULTS:The minimum mean value of platelet were(56.53?27.11)?109?L-1 after radiotherapy and chemotherapy and(126.73? 57.58)?109?L-1 after rhIL-11(Ⅰ)treatment(P
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2005
Type:
Article