Efficacy Observation of Compound Sulfur Lotion Combined with Erythromycin in the Treatment of Acne / 中国药房

ABSTRACT

OBJECTIVE:To observe efficacy of compound sulfur lotion combined with erythromycin in the treatment of acne.METHODS:100 patients with mild,moderate and severe acne were randomly divided into control group(n=50) and treatment group(n=50).Control group were treated with sulfur lotion for external use,and treatment group were given compound sulfur lotion and erythromycin for external use for 4 weeks.Each compound sulfur lotion 100 mL combined with 6 piece of erythromycin(a total of 1.5 g).Return and follow-up visit were performed once a week.The number of acne,imflammatory papule,pustule,node cyst were observed and recorded.RESULTS:Total response rate of treatment group was 76%,which was significantly higher than that of control group(38%).There were statistical difference between 2 groups(P