Analysis on Plasma Concentration Monitoring of Rifampicin and Isoniazid in Tuberculosis Patients / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-534441
ABSTRACT
OBJECTIVE:
To promote plasma concentration monitoring of anti-tuberculosis agents in the clinic.METHODS:
Results of plasma concentration monitoring of rifampicin and isoniazid in tuberculosis patients of our hospital from Aug.2005 to Dec.2008 were analyzed retrospectively.RESULTS:
Plasma concentration samples were collected from 241 patients treated with rifampicin and 53 patients treated with isoniazid 2 hours after medication.Plasma concentrations of rifampicin in 10.4% of patients were below the normal level and 31.9% were higher than the normal level.Plasma concentrations of isoniazid in 71.7% of patients were below the normal level and 15.1% were higher than the normal level.CONCLUSION:
Plasma concentration monitoring of anti-tuberculosis agents is a valuable tool to adjust the dosage of drugs,which is valuable for rational use of drugs in tuberculosis patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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