The changes of lymphocyte subpopulations in normal pregnancy and pregnancy-induced hypertention syndrome / 中国免疫学杂志

ABSTRACT

39 cases of normal pregnancy,26 cases of pregnancy-induced hypertension syndrome (PIHs) and 23 cases of nonpregnant woman were observed on the changes in B lymphocyte and T lymphocyte subpopulations.B lymphocyte were detected by direct immunofluorescent technique and T lymphocyte subpopulations were identified by rosette forming cell(RFC)treated with adnosine. Compared with the nonpregnant women,the results showed that the significant cha-nges of T lymphocyte subpopulations during pregnancy were observed including the in-crease of adenosine sensitive(AS)cells,the decrease of adenosine resistent(AR)cells,and the icrease of AS/AR ratio. Furthermore in the cases of PIHs,compared with the late pregnant women,AScells,AR cells and AS+AR cells were significantly reduced(all P value