ERYTHROCYTE SODIUM CONTENT AND SODIUM TRANSPORT IN DIABETIC PATIENTS / 中华内分泌代谢杂志

ABSTRACT

The erythrocyte sodium content and sodium transport in 50 cases of diabetic patients (NIDDM) and 26 cases of normal subjects were determined. The results showed that the sodium content of erythrocyte was obviously higher in the diabetic patients than that in the normal subjects, the activity of Na-pumps of erythrocyte was obviously lower in diabetic patients than that in normal subjects, but there was no significant difference of permeability of erythrocyte membrane to sodium observed. The changes of erythrocyte sodium content and the activity of Na-pumps of erythrocyte were obviously greater in female diabetic patients than those in male diabetic patients. The addition of insulin in vitro at a concentration of 5mg/L significantly decreased the erythrocyte sodium content and increased the activity of Na-pumps of erythrocyte in diabetic patients.