Relationship between peridontitis and prostaglandin E 2 content in gingiva and alveolar bone in guinea pigs by radioimmunoassay / 实用口腔医学杂志

ABSTRACT

20 guinea pigs were equally divided into two groups. Periodontitis was formed with silk thread suture and high sugar diet in one group; the other group was used as the control. The prostaglandin E 2 (PGE 2) in gingiva and in alveolar bone was measured with radioimmunoassay(RIA). PGE 2 level in gingiva in both groups was higher than that in alveolar bone. In the control group PGE 2 in gingiva (394.87?118.27) was 2.1 fold as much as that in alveolar bone(182.91?33.29)( P