A STUDY ON THE RELATIONSHIP BETWEEN THE CHANGES OF EXTRACELLUAR MATRIX INVADED BY COLORECTAL CARCINOMA AND ENDOTHELIAL CELLS / 中国癌症杂志

ABSTRACT

PURPOSE To investigate the relationship between the changes of extracellular matrix invaded by colorectal carcinoma and vascular endothelial cells,which will be useful to understand colorectal carcinoma biological behavior and may have clinical significance in the treatment of colorectal carcinoma.METHODS Immunohistochemistry technique and semi quantitative analysis were used.RESULTS As to the changes of ECM and endothelial cells,there were significant differences among the paracarcinoma groups,different invasive groups and normal group.THe increase of LN,CD34,F8 and actin were correlated with colorectal carcinoma invasion( P