Interference effect of Anisodamine on plasma endotoxin cousing renel damage in patients with obstractive jaundice / 中国现代普通外科进展

ABSTRACT

Objective: To study the plasma endotoxin(ET)on renal damage and clinical interference of anisodamine in patients with obstractive jaundice(OJ).Methods: Thirty patients with OJ were randomly divided into general treatment group(A group) and anisodamine treatment (B jroup).The level of plasma ET and endogenous creatinine clearance rate(Ccr) were determined at perioperative period,other 21 cases of chronic choelithiasis without jaundice were employed to serve as the control.Results: (1)The plasma ET level of peripheral blood was increased significantly and Ccr level was decreased markedly in both A and B group than in the control at lst day of hospitalization(P