STUDIES ON THE ENHANCING EFFECT OF FOUR INTERFERON INDUCTION PROMOTERS / 解放军医学杂志

ABSTRACT

This paper reports four enhancing agents of interferon induction promoter in promoting induction of Namalwa cell interferon. In addition to the confirmation of the effects of the previously reported sodium butyrate and BrdU in raising interferon production by Namalwa cells, our study also shows that Acanthopanax senticosus polysaccharide, a classical Chinese herb medicine and sodium carboxyme- thyl starch possess the property of enhancing interferon production. When Namalwa cells are pre-treated with these two preparations, the mean titre of interferon is increased to 5 folds and 8-20 folds respectively. Possible operative mechanisms of this enhancement are discussed.