Expression of matrix metalloproteinase-9(MMP-9) and tissue inhibitor of metalloproteinase-1(TIMP-1) in gastric carcinoma / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)1999.
Article
in Chinese
| WPRIM
| ID: wpr-535905
ABSTRACT
Objective:
To explore the expression and significance of MMP-9 and TIMP-1 in gastric carcinoma.Methods:
S-P immunohistochemical method was used to examine the expression of MMP-9 and TIMP-1 in 47 specimens of gastric carcinoma.Results:
MMP-9 and TIMP-1 were expressed predominantaly in the peritumor stromal cells than tumor cells themselves.The expression level of MMP-9 and TIMP-1 correlated with lymph node metastasis (P0 05).Conclusion:
The results suggests that MMP-9 and TIMP-1 might be important biological makers for determining the malignant behave of gastric carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Current Advances in General Surgery
Year:
1999
Type:
Article
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