The relationship between large multifunctional proteasome 7 gene polymorphism and susceptibility of type 1 diabetes mellitus / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12)1986.
Article
in Zh
| WPRIM
| ID: wpr-536038
Responsible library:
WPRO
ABSTRACT
Objective To study the relationship between large multifunctional proteasome (LMP) 7 gene polymorphism and susceptibility of type 1 diabetes mellitus (DM). Methods The genotyping of LMP7 gene was determined by polymerase chain reaction restriction fragment length polymorphism (PCR RFLP) in 71 type 1 DM patients and 86 healthy persons (as controls). Furthermore, the type 1 DM patients were divided into 3 groups according to the age of diabetic onset. Group A was ≤14 years, group B 15~30 years, group C≥31 years.Results The frequency of LMP7 B/B was decreased significantly (39% vs 58%, P
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
1986
Type:
Article