Neurotensin Involved in Electroacupuncture Analgesia / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)1985.
Article
in Chinese
| WPRIM
| ID: wpr-536197
ABSTRACT
Experiments were undertaken in rats to investigate the effect of intraventrical injection of neurotensin (NT) and antineurotensin serum (ANTS) on electroacupuncture (EA) analgesia. Neurotensin administration induced a enhancement of pain threshold and increased electroacupuncture analgesia Injection of antineurotensin serum reduced the pain threshold significantly and diminished the effect of electroacupuncture analgesia. Furthermore, pre-injection of naloxone 100?g intraventrically could weaken analgesic effect of NT and NT-EA analgesia. These results indicate that neurotensin in central nervous system is involved in pain modulation and plays a role in EA analgesia The effect of neurotensin may be partly conducted by endogenous opiate peptides.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
1985
Type:
Article
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