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Continuous infusion of fluorouracil lasting 240 hours in 35 cases with gastric cancer / 中国癌症杂志
China Oncology ; (12)1998.
Article in Chinese | WPRIM | ID: wpr-536597
ABSTRACT

Purpose:

To study the clinical response and the toxic-side reactions of patients with gastric cancer treated with continuous infusion of fluorouracil (5-FU) lasting 240 hours.

Methods:

35 cases of gastric cancer were treated with continuous infusion of 5-FU lasting 240 hours.32 cases of gastric cancer were treated with traditional infusion of 5-FU on days 1 to 5. The clinical response and the toxic -side reactions were observed.

Results:

35 cases were treated with continuous infusion of 5-FU regimen with a response rate of 51.4%. 32 cases were treated with traditional infusion of 5-FU regimen with a response rate of 25.0%,thus between them,there was a significant difference in curative effects. The toxicities in traditional infusion of 5-FU group were more severe than in continuous infusion of 5-FU group. They included myelosuppression nausea et al.

Conclusions:

Continuous infusion of 5-FU regimen is preferable in the treatment of gastric cancer.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Oncology Year: 1998 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Oncology Year: 1998 Type: Article