Continuous infusion of fluorouracil lasting 240 hours in 35 cases with gastric cancer / 中国癌症杂志
China Oncology
;
(12)1998.
Article
in Chinese
| WPRIM
| ID: wpr-536597
ABSTRACT
Purpose:
To study the clinical response and the toxic-side reactions of patients with gastric cancer treated with continuous infusion of fluorouracil (5-FU) lasting 240 hours.Methods:
35 cases of gastric cancer were treated with continuous infusion of 5-FU lasting 240 hours.32 cases of gastric cancer were treated with traditional infusion of 5-FU on days 1 to 5. The clinical response and the toxic -side reactions were observed.Results:
35 cases were treated with continuous infusion of 5-FU regimen with a response rate of 51.4%. 32 cases were treated with traditional infusion of 5-FU regimen with a response rate of 25.0%,thus between them,there was a significant difference in curative effects. The toxicities in traditional infusion of 5-FU group were more severe than in continuous infusion of 5-FU group. They included myelosuppression nausea et al.Conclusions:
Continuous infusion of 5-FU regimen is preferable in the treatment of gastric cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
1998
Type:
Article
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