Bilateral Serous Retinal Detachment as a Presenting Sign of Acute Lymphoblastic Leukemia
Korean Journal of Ophthalmology
;
: 245-248, 2010.
Article
in English
| WPRIM
| ID: wpr-53669
ABSTRACT
We present a case of bilateral serous retinal detachment (SRD) as a presenting sign of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). A 45-year-old woman presented with decreased vision and was found to have bilateral serous retinal detachment. Peripheral blood smears revealed leukocytosis of 53.9x10(3)/microliter with 64.6% lymphoblasts. A bone marrow aspirate revealed the presence of lymphoblasts. Cytogenetic and molecular genetic analysis detected a reciprocal translocation between chromosome 9 and 22, t(9;22) (q34;q11). A diagnosis of Ph+ ALL was made. Following systemic chemotherapy, the bilateral SRD resolved completely with full recovery of vision. The sudden appearance of SRD should raise suspicion for leukemia. Prompt recognition of this disease is important for early systemic treatment and restoration of visual function.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Retinal Detachment
/
Fluorescein Angiography
/
Visual Acuity
/
Follow-Up Studies
/
Recovery of Function
/
Tomography, Optical Coherence
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Fundus Oculi
/
Antineoplastic Agents
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2010
Type:
Article
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