Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes
Korean Journal of Ophthalmology
;
: 213-218, 2010.
Article
in English
| WPRIM
| ID: wpr-53675
ABSTRACT
PURPOSE:
To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs).METHODS:
Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V(postop), logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced.RESULTS:
V(postop) was determined to be significantly correlated with the preoperative visual acuity (V(preop)) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V(postop) was derived from the most accurate regressionanalysis:
V(postop)=0.248xV(preop)+1.1x10(-6)xA(2)-0.121xD+0.19.CONCLUSIONS:
The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Retinal Perforations
/
Vitrectomy
/
Visual Acuity
/
Cell Survival
/
Retrospective Studies
/
Follow-Up Studies
/
Photoreceptor Cells, Vertebrate
/
Tomography, Optical Coherence
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS