Observation of senile osteoporosis treated by calcitonin / 中华老年医学杂志

ABSTRACT

Objective To observe the effect of calcitonin on senile osteoporosis. Methods Eighty-six osteoporotic patients diagnosed by double-energy X-ray absorptiometry and manifested clinical symptoms and with spinal bone mineral density (BMD) 2 or more were divided into two groups 46 patients in the observed group were administered 100 IU calcitonin once a day for three days, and changed to 50IU calcitonin once every other day for one month; repeat the administeration method after one month rest and plus oral calcium carbonate vitamin D 600 mg every day for a period of 6 months; another 40 patients in the control group only took calcium carbonate vitamin D 600 mg every day for 6 months. The BMD of L1-4 and hips was examined before and after treatment. Results Bone pain relieving was more obviously in the observed group than that in the control group. BMD of the lumbar spine in the observed group showed remarkable change after treatment(P