Effect of Movement Restrict on the Expression of 5-HT Receptor Subtypes in Rat Brain / 中国临床心理学杂志
Chinese Journal of Clinical Psychology
;
(6)2001.
Article
in Chinese
| WPRIM
| ID: wpr-538311
ABSTRACT
Objective:
To explore the 5-HT mechanism of stress .Methods:
The method of polymerase chain reaction (PCR) was used to detect the presence of 5-HT receptor subtypes in the hippocampus,hypothalamic and midbrain of the rat after 30days of movement restrict compared with normal cage control groups (CC) . The specific oligonucleotide primers were synthesized based on the complementary DNA sequence for each of the rat 5-HT 1A and 5-HT 2A receptor subtypes .Results:
The expression of 5-HT 1A receptor subtypes in each regions of the rat brain after movement restrict were signifcantly lower than that of the CC groups, and the expression of 5-HT 2A receptor subtype were signifcantly higher( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Psychology
Year:
2001
Type:
Article
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