ERYTHROCYTE MEMBRANE CARBOHYDRATES, LIPIDS AND Ca~(2+)-Mg~(2+) ATPase IN DUCHENNE MUSCULAR DYSTROPHY / 第二军医大学学报

ABSTRACT

The carbohydrate and lipid contents and Ca2+-Mg2+ ATPase activity of erythrocyte membrane were studied in 10 patients with DMD. The results demonstrated that the sialic acid content was markedly decreased, and the neutral sugar content normal. The cholesterol was significantly increased, but the phospholipids unchanged, resulting in a significantly reduced P/C ratio. The activity of Ca2+-Mg2+ ATPase elevated markedly. The study suggests that the erythrocyte membranes with DMD are altered both in composition and function.