The impact of cell period and cell surface antigen in cervical cancer cell lines by interferon-? gene transfer / 中国癌症杂志
China Oncology
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-539823
ABSTRACT
Purpose:
To explore the tumor cell responses after IFN-? gene transfer by analyzing the expression of cell surface antigen,apoptosis and the impact of cell period.Methods:
We constructed IFN-? gene expression vector-pcDNA3- IFN-?, and transfected it into HeLa cell lines by Lipofectamine. The expression of IFN-??the Human Leukocyte antigen(HLA-DR) after gene transfer were measured. The apoptosis of tumor cells and the variety of cell period were also measured to investigate the anti-tumor mechanism by IFN-? gene therapy.Results:
The results showed that the HLA-DR expression in Hela cell lines increased significantly(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
2001
Type:
Article
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