Effect of angiotensin Ⅱ receptor antagonist on the plasma levels of calcitonin gene-related peptide and endothelin in the patients with diabetic nephrophy / 中华内分泌代谢杂志

ABSTRACT

The plasma levels of calcitonin gene-related peptide (CGRP) and endothelin (ET) were assayed in 76 patients with diabetic nephropathy (DN) and 23 healthy subjects, and the changes of CGRP and ET levels after treatment with angiotensin Ⅱ receptor antagonist (ARBS) were observed. The results showed that CGRP level was increased and ET level decreased after treatment with ARBS, which seemed to delay the onset and development of DN.