Experimental Study on Lung Cancer Induced by Cooking Oil Fumes in SD Rats / 环境与健康杂志
Journal of Environment and Health
;
(12)1992.
Article
in Chinese
| WPRIM
| ID: wpr-540914
ABSTRACT
0.05). The pulmonary carcinoma incidence rate of the rats treated at the dosages of (6.88?0.31) mg/m3, (15.06?0.35) mg/m3 and (35.33?1.69) mg/m3 were 6.56%?8.96% and 12.70% respectively. Immunohistochemical staining showed that COF could induce abnormal expression of p53 and FHIT protein in lung tissue. Only in experimental group the positive expression of mutant p53 protein located in bronchi epithelial cell nucleus were found. The positive expression rate of p53 protein in lung tissue section of tumor cases was significantly higher than that of control group(P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Environment and Health
Year:
1992
Type:
Article
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