Effects of chemotherapy with gemcitabine in advanced non-small-cell lung cancer elderly patients / 中国癌症杂志

ABSTRACT

Purpose:To observe the effective of gemcitabine in elderly patients(pts) with advanced non-small-cell lung cancer(NSCLC), compared to supportive care alone. Methods:Gemcitabine group (n=21), received gecitabine (1 250) mg/m~(2), on days 1 and 8,using 21-day schedule, total 4 cycles. Control group (n=23) , using supportive care alone. Results:The overall response rate of gemcitabine group was 28.6%, 6 had partial response(PR), 12 had stable disease(SD),3 had progression disease(PD).No patient had complete responses (CR) and PR in control group. The median duration of response was 6.3 months in gemcitabine group, the median survival was 12.8 and 4.6 months respectively (P