Application of ~1H magnetic resonance spectroscopy in diagnosis and differential diagnosis for bacteroidal brain abscesses / 中华神经科杂志

ABSTRACT

Objective To show the distinctive resonance pattern in 7 cases of intracranial abscess and 19 cases of cystic lesions as to evaluating these specific resonance peaks. Methods Characteristics of ~1H-MRS in 7 patients with brain abscesses and 19 with cystic or necrotic intracranial tumors were analyzed and compared. Peak assignment was based on reference values from in vivo and in vitro studies. Results Among 7 patients with brain abscesses, 6 showed the presence of cytosolic amino acid (AA) at 0.9 ppm, 5 showed alanine (Ala) at 1.5 ppm, 2 showed acetate (Ac) at 1.9 ppm and 1 patient showed succinate (Suc) at 2.4 ppm. None of the above resonances had been detected in spectra from 19 cases of cystic or necrotic intracranial tumors. Conclusions ~1H-MRS might reflect the different histochemical specificity of abscesses and cystic or necrotic tumors effectively. It should have special values in diagnosis and differential diagnosis of the brain abscess.