The detection and analysis of etiology of non-bacterial pneumonia in children in Xi'an / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the etiological characteristics of non-bacterial pneumonia in children in Xi'an. Methods Virus IgM antibody was detected by solid phase ELISA technique, and mycoplasma pneumonia(MP) IgM antibody was detected by Au-mark immunodotting technique. Results In a total of 302 cases, mycoplasma pneumonia and / or virus were detected in 204, with the positive infection rate as 67.55%(204/302); 328 cases were found with positive strains of pathogens including 120 mycoplasma(MP) strains (36.6%) among which were 77 coxsackie virus(CV) strains (23.5%), 56 respiratory syncytial virus(RSV) strains (17.1%), 39 influenza virus strains(11.9%), 25 adenovirus strains(7.6%) and 11 EBV strains(3.4%). The single infection rate was 51.99%(157/302) while the mixed infection rate was 15.56%(47/302). The onset of non-bacterial pneumonia in Xi'an could be seen in all seasons of the year. There was significant seasonal difference among the incidences caused by different pathogens(P0.05). The highest incidence age was between 7 months to 3 years. Conclusion MP, CV, RSV are the leading pathogens that cause non-bacterial pneumonia in children in Xi'an. ELISA and Au-mark immunodotting techniques are simple and quick to detect viruses and mycoplasma.