The clinical characteristics of different pathological subtypes of cyst-associated renal cell carcinoma / 中国癌症杂志

ABSTRACT

Purpose:To study the pathological and clinical characteristics of different subtypes of cyst-associated renal cell carcinoma and summarize the experience in diagnosis and therapy. Methods:39 cases with cyst-associated renal cell carcinoma underwent urological operations in our hospital from 1991 to 2000. Their medical data were analyzed and then divided into different subtype according to pathological characteristics. Results:The data included 2 patients with renal cell carcinoma on the background of polycystic kidney, 20 cases with renal cell carcinoma originating in a cyst and 17 cases with cystic renal cell carcinoma.3 patients underwent partial nephrectomy and 36 cases unilateral radical nephrectomy.16 patients were Robson stage Ⅰ and 23 were RobsonⅡstage.The pathological diagnosis was 38 cases of clear cell carcinoma and one of chromophobe cell carcinoma. The survival rates at 1,3,5 years are 100%、100%、94.8%(37/39) respectively after follow-up. Conclusions:The cases with renal cyst need periodical health check-up.Most of cyst-associated renal cell carcinomas belong to low stages. Contrast-enhanced computed tomography and selective digital subtraction angiography of renal artery are the main methods for preoperative clinical diagnosis. The long-term effect of operations of cyst-associated renal cell carcinoma is better.