Detection of human herpesvirus antibodies 6 in Changchun city / 中国免疫学杂志

ABSTRACT

Objective:To establish an indirect immunofluorescence assay for detection of serum IgG antibody against HHV-6,and to detected antibodies of HHV-6 in Changchun city.Methods:Cord blood mononuclear cells infected by HHV-6 strain GS were used to prepare cell antigen slide so as to establish an IFA and was used detect the HHV-6 antibody level in serum for Changchun city population.Results:An indirect immunofluorescence assay was established for detection of serum IgG antibody against HHV-6,at the same time the HHV-6 antibody level in serum for Changchun city population have been detected,and positive rate of HHV-6 antibody was 65.2%.Conclusion:A specific IFA has been established successfully for the investigation of HHV-6 infection.