Inhibitive effect of TNP-470 on vasculogenic mimicry in gastric cancer cell line SGC-7901 in vitro / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)1999.
Article
in Chinese
| WPRIM
| ID: wpr-541718
ABSTRACT
Objective:
To investigate the effect of TNP-470 on the vasculogenic mimicry in gastric cancer cell line SGC-7901 in vitro.Methods:
Cultured SGC-7901 cells were devided into TNP-470 group and control group.The effect of proliferation,invasion and tube formation on SGC-7901 cells were detected by colone formation assay,invasion assay and tube formation assay respectively in vitro.Results:
Number of colone formation of TNP-470 group was not significantly lower than the control group(P0.05),the number of cells which crossed to the lower surface of the matrigel-coated filters in TNP-470 group was significantly lower than the control group(P0.01).Tube formation could be inhibited by TNP-470.Conclusion:
TNP-470 can inhibit the vasculogenic mimicry formation of gastric cancer cell line SGC-7901 in vitro.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Current Advances in General Surgery
Year:
1999
Type:
Article
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