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Relationship of oncogene survivin、c-erbB-2 expression in breast cancer and its prognostic significance / 中国癌症杂志
China Oncology ; (12)2001.
Article in Chinese | WPRIM | ID: wpr-541995
ABSTRACT

Purpose:

To investigate the expression of oncogene survivin,c-erbB-2 in breast cancer and its prognostic significance.

Methods:

Detect the expression of survivin,c-erbB-2 in 80 case breast cancer tissues by immunohistochemistry S-P method,analyze its correlation with axillary lymph node metastasis and 5-year disease free survival(DFS).

Results:

Survivin gene positive expression rate was 68.75%(55/80),c-erbB-2 gene positive expression rate was 36.25%(29/80) in breast cancer tissues,all have positive correlation with the axillary lymph nodes metastasis but negative to 5 years DFS(P0.05);survivin and c-erbB-2 genes expression have positive correlation(P

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: China Oncology Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: China Oncology Year: 2001 Type: Article