Effect of Intracellular Glutathione in Relieving the Cytotoxicity Induced by Arsenic / 环境与健康杂志
Journal of Environment and Health
; (12)1993.
Article
in Zh
| WPRIM
| ID: wpr-542402
Responsible library:
WPRO
ABSTRACT
Objective To study the effect of cellular glutathione (GSH) in relieving the cytotoxicity induced by arsenic on HaCaT. Methods The HaCaT cells were pre-treated with N-acetylcysteine (NAC) and L-buthionine-[S'R]-sulfoximine (BSO) for 24 h, then treated with sodium arsenite (NaAsO2) by adding it into the medium for 24 h. Alarmarblue assay was used to detect the proliferation of the cells. Results The reduction rate of Alarmarblue increased when the HaCaT cells were treated with 0.001-10.000 ?mol/L of NaAsO2 alone (P
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Environment and Health
Year:
1993
Type:
Article