Protective effect of traditional Chinese medicine like Dansen and western medicine on traumatic brain edema / 中华创伤杂志

ABSTRACT

Objective To evaluate the effects of traditional Chinese medicine likeDansen and western medicine in treating traumatic brain edema (TBE). Methods A total of 130 Wistar rats were divided randomly into six groups Group A (normal contrast group), Group B (operation group), Group C (western medicine treatment group, WM group), Group D (western medicine and salvia injection), Group E (western medicine and Honghua injection) and Group F (western medicine and Sanqi injection). The model of brain edema was established by liquid nitrogen treatment to assay whole blood viscosity, water content and Even blues (EB) in brain tissues and to observe the content and pathologic changes of endothlin (ET) in plasma. Results Whole blood viscosity of Groups D, E and F was lower than that of Group B (P0.05). Water content and EB in brain tissues and ET of plasma in Groups C, D, E and F were lower significantly than those in Group B (P