Clinical research on the relationship between iodine and autoimmunity thyroid disease / 西安交通大学学报(医学版)

ABSTRACT

Objective To observe the iodine state of patients with autoimmunity thyroid disease(AITD) in Shaanxi province,and to discuss the relationship between the metabolism of iodine and the occurrance,development and prognosis of AITD.Methods A total of 388 cases were collected,among whom 283 were patients with AITD,and 105 were patients with non-AITD.Questionnaires were designed to determine the general state of the patients,the size,shape and texture of the thyroid,the urinary concentration of iodine,the function of thyroid and the autoantibody of thyroid.The data were processed by SPSS12.0.Results The mean urinary concentrations of iodine in patients with GD,with HT,and the control group were 212?g/L,245.4?g/L,and 197.8?g/L respectively,which were statistically different.In the HT group,wich different urinary concentrations of iodine,there were no statistical difference of TGAb,TMAb,and HS-TSH.Conclusion Excessive in-take of dietary iodine may be related with AITD.