Effect of mRNA expression of COX-2 and MMP-2 on the invasion and metastasis of bladder cancer and their correlation / 肿瘤研究与临床
Cancer Research and Clinic
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-544024
ABSTRACT
Objective To investigate the mRNA expression of COX-2 and MMP-2 on transitional cell carcinoma of bladder(TCCB) and their relationship with the invasion and metastasis of the bladder neoplasm. Methods Surgical bladder specimens were obtained from 54 TCCB patients and 5 benign prostate hyperplasia (BPH) patients to make paraffin slices, and 8 specimens which against cancers. In situ hybridization (ISH) was used to assay the mRNA expression of COX-2 and MMP-2. Results The mRNA expression of COX-2 and MMP-2 in bladder neoplasm were 59.2 % and 57.4 % respectively. Compared to the control, their expression was higher (P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2006
Type:
Article
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