The effect of lipoxygenase inhibitor (NDGA) on the expression of VEGF and CD44V6 in breast cancer MCF-7 cells / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)2004.
Article
in Chinese
| WPRIM
| ID: wpr-544054
ABSTRACT
Objective:
To explore the effects of VEGF and CD44V6 on breast cancer MCF-7 cells by NDGA.Methods:
MCF-7 cells in the logarithmic growth state were selected and measured.There were four cell groups(concentration0,1,10,100?mol/L)in the experiment.After 48h treatment of NDGA,the expression of VEGFmRNA was measured by RT-PCR and the expression of CD44V6 was examined by flow cytometry.Results:
After treatment of NDGA,the expressions of VEGFmRNA and CD44V6 in NDGA groups were significantly lower than that of the control group(F=2996.13,P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Current Advances in General Surgery
Year:
2004
Type:
Article
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