Expression and significance of hepatocyte growth factor and c-Met in bladder transitional cell carcinoma / 中华泌尿外科杂志
Chinese Journal of Urology
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-544097
ABSTRACT
Objective To determine the expression of hepatocyte growth factor and its receptor c-met in bladder transitional cell carcinoma, and to investigate correlations of the expression and clinic features of the tumor. Methods Samples of 45 human bladder carcinoma and 8 normal bladder tissues were detected with immunohistochemical method for HGF and c-met ,then relationships between the expressions and clinic features of the tumor were analyzed. Results There was no HGF expression and only 1 weak positive c-met expression in the normal urinary bladder tissues. While in bladde cancer specimens, positive expression rates of HGF and c-met were as high as 64.4%,62.2%, respectively.Coexpression rate of HGF and c-met was 42.2%. The positive rates were significantly higher in BTCC specimens than in normal tissues (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Urology
Year:
2006
Type:
Article
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