Expression of P53 protein in oral tumor tissue in smoking and nonsmoking subjects / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2001.
Article
in Chinese
| WPRIM
| ID: wpr-544535
ABSTRACT
Objective:
To study the relationship between smoking and P53 protein expression in oral tumor tissue.Methods:
The expression of P53 protein in oral tumor tissue was detected in 22 smoking cases and 32 nonsmoking cases by immunohistochemical SP method. SAS software was used for statistic analysis.Results:
The positive expression rate of P53 protein in smokers (90.91%) was higher than that in nonsmokers (46.88%,P0.05).Conclusion:
Smoking may stimulate the mutation of p53 gene and play an important role in the carcinogenesis of oral tissues.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2001
Type:
Article
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