Effect of astragalus complanatus on liver free radical metabolism in rats of exercise training / 西安交通大学学报(医学版)

ABSTRACT

Objective To study the effect of astragalus complanatus on the metabolism of free radicals in liver and exercise performance in models of exhaustive training rats.Methods After 7 d adaptive training,we randomly divided rats into three groups quiet control group(A),sport training group(B) and astragalus complanatus training group(C).We measured rat liver indices such as the activities of total superoxide dismutase(T-SOD),glutathione peroxidase(GSH-Px),catalase(CAT) and content of malonaldehyde(MDA).Results The activity of astragalus complanatus groups(C) T-SOD(78.17?0.17),GSH-Px(35.42?1.68) and CAT(17.61?0.05) in liver tissue increased and the content of MDA(6.70?0.53) decreased remarkably compared with that in sport training group(B).Conclusion As an efficient free radical scavenger,astragalus complanatus can strongly enhance anti-oxidative status and improve exercise performance in trained rats.