Influence of ~(131)Ⅰ on gonadal gland in the treatment of hyperthyroidism / 中华内分泌代谢杂志

ABSTRACT

Gonadal gland is one of the highly sensitive organs to ionizing radiation,but there is a threshold dose for gonadal sterility caused by ionizing radiation.When ~(131)Ⅰis applied in the treatment of patients with hyperthyroidism,the usually absorbed radiation dose of gonadal gland is below the threshold.It is documented that ~(131)Ⅰtherapy for fertile women or adolescents and children with hyperthyroidism does not cause reduction in fertility and does not increase the incidence of genetic defects.Therefore ~(131)Ⅰtherapy,for adolescents and children with hyperthyroidsm,who have been failed in anti-thyroid drug therapy,refused surgical treatment or were contraindicated in surgery,is another better available therapeutical modality.