Effects of epidural ethanesulfonic acid ropivacaine combined with fentanyl on stress response in the operation of hypogastric zone / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the effects of epidural ethanesulfonic acid ropivacaine combined with fentanyl on stress response in the operation of hypogastric zone.Methods Sixty patients(ASAⅠ-Ⅱ) scheduled for the operation on hypogastric zone were divided randomly into two groups.Epidural puncture and catheterization were carried out routinely and 8.94 g/L ethanesulfonic acid ropivacaine(control group) and that with 0.1mg fentanyal(research group) was used for epidural block.Blood pressure,heart rate,adrenaline,noradrenaline,cortisol,insulin and blood sugar level at defined time were measured and compared.Results 60 min and 90 min after skin incision,the levels of adrenaline,noradrenaline and cortisol in the blood were higher than those before the operation(P0.05),but increased significantly in the control group(P