Interface characteristics and mechanism analysis of osteointergration between bone tissues and surface porcelainized titanium implants / 实用口腔医学杂志

ABSTRACT

Objective:To evaluate osteointegration condition and mechanism of surface porcelainized titanium implants(Bio-Ti implant) by studying the characteristics of implant-bone interface. Methods: Edentulous mandible models of dogs were established. Pure titanium implants were designed for in vivo experiments. Bio-Ti implants were installed in dogs' mandible. All animals were sacrificed in 3, 6, 12 weeks respectively. Osteoid deposition on implants surface was observed and analyzed by SEM and EDX. Bone-implant interface of holistic specimen was analyzed by element linear scanning. All procedures were under the control of pure titanium implants. Results: Relatively great quantity of osteoid deposition could be found around Bio-Ti implants in 3 weeks, with tight combination with implants. Bio-Ti implant surface was found to have been reconstructed, Ca and P content markedly increased in partial exposed implant surface by SEM element analysis, with osteoid granules deposited inside micropores. Linear and planar scanning results showed no component breaks in the area along from bone tissue to implant, which suggested mutual infiltration and integration between implants and bone tissues. Conclusion: Bio-Ti implants can induce early osteoid deposition in vivo and chemically combine with bone tissues, within the period of markedly shortened osteointegration duration.