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Immunological analysis of the swine vesicular disease virus (SVDV) recombinant P1 protein in Guinea pigs / 中国免疫学杂志
Chinese Journal of Immunology ; (12)2001.
Article in Chinese | WPRIM | ID: wpr-546565
ABSTRACT

Objective:

To investigate the immunogeneicity of a subunit vaccine of capsid protein precursor(P1) of swine vesicular diseas(SVD).

Methods:

In this study,the guinea pigs were immunized with the home-made antigen,T-lymphocyte proliferation response,blocking ELISA and micro-neutralization assay were used to detect the effect of the immunized responses in guinea pigs.

Results:

The results indicated that a retroviral-based vaccine carrying the capsid protein precursor(P1) of SVD was able to elicit strong SVDV-specific humoral immune responses in guinea pigs.

Conclusion:

It encourages further work towards the development of a vaccine against SVDV infection.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Immunology Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Immunology Year: 2001 Type: Article