Joint Effect of Cerium on MDA Content and DNA Damage Incused by Cadmium in Loach Liver / 环境与健康杂志

ABSTRACT

Objective To study the protective effect of cerium on changes of MDA content and DNA damage induced by cadmium in loach liver.Methods The loaches were randomly divided into control group and low (0.025 mg/L),moderate(0.25 mg/L),high(2.5 mg/L)Cd~(2+) exposed group and low(0.025 mg/L Cd~(2+)+0.025 Ce~(3+)),moderate(0.25 mg/L Cd~(2+)+0.25 mg/L Ce~(3+)),high (2.5 mg/L Cd~(2+)+2.5 mg/L Ce~(3+))CdE~(2+)+Ce~(3+) exposed group,the MDA content in loach liver was determined at 1d,2d,3d,5d,7d and 10 d of exposure with the method of TBA,the MDA damage in loach liver was detected at 7 d with the method of agarose gel electrophoresis.Results The MDA content of low Cd~(2+) exposed group was higher than that in the control at ld and 2 d (P