Evaluation of White Matter Trajectories using MR Diffusion Tensor Tractography in Brain Tumors / 实用放射学杂志

ABSTRACT

Objective To study the value of MR diffusion tensor tractography(DTT) in evaluating the white matter(WM) tracts in cerebral neoplasm.Methods Fiber tractography was used in this study to assess tumour-induced changes in WM trajectories in three cases of cerebral neoplasm glioblastoma multiforme, meningioma and anaplastic astrocytoma.Results Three patterns of WM alteration were identified(1) disruption;(2) displacement and (3) infiltration. Tumor disruption of WM tracts was observed in glioblastoma multiforme, in which the terminated fibers could crossed the corpus callosum. In meningioma, DTT illustrated bulk displacement ,remnant and separation of WM tracts.In anaplastic astrocytoma,WM tracts were disrupted and infiltrated by tumors. Conclusion The changes of WM tracts on DTT are correlated with the clinical and histopathological features of the tumor.