Bone and Soft Tissue Tumors:Study of 3.0T ~(31)P MR Spectroscopy / 实用放射学杂志

ABSTRACT

Objective To study the characteristics of 31P-MR spectroscopy(31P-MRS) of benign and malignant bone and soft tissue tumors at 3.0 Tesla MR scanner.Methods 41 patients with bone and soft tissue tumors confirmed pathologically were examined with31P-MRS at 3.0 Testa MR scanner using phosphorus surface coil.The areas under the peaks of various metabolites in spectra were measured.The ratios of the other metabolites to ?-ATP,NTP and phosphocreatine(Pcr) were calculated.Intercellular pH was calculated according to the chemical shift change of inorganic phosphours(Pi) relative to Pcr.Acoording the area under the peak,the ratios of other metabolite including phosphomonoester(PME)/?-ATP,phosphodiester(PDE)/?-ATP,?-ATP/Pi,PME/NTP,PDE/NTP,Pcr/Pi and Pcr/PME related to ?-ATP,NTP(NTP=ATP+Pi+Pcr) and Pcr were calculated and dealt with SPS11.5 for Windows software package statistically through the nonparameter test of several independent samples.Results The ratios of Pcr/PME and PME/NTP in benign and malignant tumors were significantly different from those of the normal group(P