Protective effects of adeno-associated viral gene transfer of BDNF on the hippocampal neurons / 中国免疫学杂志
Chinese Journal of Immunology
;
(12)1999.
Article
in Chinese
| WPRIM
| ID: wpr-547053
ABSTRACT
Objective:
To investigate the effective mechanism for transfection of rat brain derived neurotrophic factor(BDNF) gene by recombinant adeno-associated virus in the cultured hippocampal neurons.Methods:
rAAV-BDNF was injected into the serum free-induced neurons.DAPI,PI and Actin stain was performed to measure the apoptosis cells and morphogenesis of the cells.Results:
After the gene transfer,the survival rate of the serum free-induced neurons was increased by 65%.Conclusion:
The recombinant adeno-associated virus vector can protect the serum free-induced neurons from Apoptosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
1999
Type:
Article
Similar
MEDLINE
...
LILACS
LIS