Animal experimental study of fracture fixation with PDLLA mixed with chitosan / 中国矫形外科杂志
Orthopedic Journal of China
;
(24)2006.
Article
in Chinese
| WPRIM
| ID: wpr-547113
ABSTRACT
[Objective]To explore the effect of fracture healing with intramedullary nail of poly-DL-lactic acid(PDLLA) mixed with chitosan and basic fibroblast growth factor(b-FGF),and provides the basis for clinical application.[Method]Middle tibia fracture model of 120 healthy adult rabbits of New Zealand were established and randomly divided into 6 groups as followsexperimental(A)30 rabbits with PDLLA+CHS+ b-FGF;control5 groups(18 animals for each group)control(B) with PDLLA+CHS,control(C) with PDLLA,control(D) with PDLLA+b-FGF,control(E) with Kirschner's wire,and control(F) with Kirschner's wire+b-FGF.Radiological and histological follow-up was performed in 4,8,12 weeks postoperatively.[Result]All animals were survival.There was no significant difference(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Orthopedic Journal of China
Year:
2006
Type:
Article
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