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Method for calculating the blood concentration of isoflurane with the inspired and expired concentrations during laparoscopic surgery / 中国现代普通外科进展
Article in Chinese | WPRIM | ID: wpr-547503
Responsible library: WPRO
ABSTRACT

Objective:

To estimate the blood concentration of isoflurane with the inspired andexpired concentrations during laparoscopic surgery.

Methods:

2 sections were divided in this experiment section 123 adult patients (ASA I~II)were received abdominal surgeries,of whom,12 patients for non-laparoscopic surgeries and the others for laparoscopic surgeries. Central venous blood samples were collected for gas chromatography determination 20, 40, 60, 80 min after inhalating isoflurane . We could receive two different F value (the fraction of uptake of isoflurane)through the formula. Section 2 27 patients were recruited for abdominal surgeries, 13 for laparoscopic surgeries and the others for non-laparoscopic surgeries. All of the processes were the same as the former. Then we confirm the results obtained from section1.

Results:

The F was 0.52 in the laparoscopic surgeries and 0.44 in the nonlaparoscopic surgeries. In the laparoscopic surgeries, the bias (MDPE) was 17% , accuracy (MDAPE)was 22.88% and the wobble was 11.7% .The correlation coefficient (r)was 0.83. In the nonlaparoscopic surgeries, the MDPE was 5.37% , the MDAPE was 16.02% , the wobble was 15.86% .The correlation coefficient was 0.90.

Conclusion:

The formula could be used in abdominal surgeries to evaluate the concentration of isoflurane according to the clinical standard of MDPE

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Current Advances in General Surgery Year: 2004 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Current Advances in General Surgery Year: 2004 Type: Article