Study of risk factors in renal involvement in children Henoch-Schonlein purpura / 中华疾病控制杂志

ABSTRACT

Objective To analyze children Henoch-Schonlein purpura of nephral involvement factors.Methods 212 cases of children hospitalized with HSP from Jan 1,2007 to Dec 31,2007,were divided into purpura nephritis(HSPN) and non-nephritis groups.Such factors as gender,age,clinical and laboratory tests were dealt with by single-and multi-variable analysis.Results ①96 cases(45.28%) in HSP were with kidney damage,92.71% HSPN children with abnormal urine test within 3 months.②Symptoms of severe rash,skin rash repeated in three months ≥3 times,persistent severe abdominal pain and severe joint involvement were closely related to the occurrence of HSPN.Logistic regression analysis had statistical significance(P