CYP2C9*3 and MSA2756G gene polymorphisms in patients with hyperlipemia in Ningxia Hui population / 西安交通大学学报(医学版)
Journal of Xi'an Jiaotong University(Medical Sciences)
;
(6)2004.
Article
in Chinese
| WPRIM
| ID: wpr-548892
ABSTRACT
Objective To investigate the distribution of CYP2C9*3 and methionine synthetase(MSA2756G) genes related to drug therapy in hyperlipidemia patients of Ningxia region as well as its relation with hyperlipidemia.Methods Genotype was determined by using amplication-created restriction sites(ACRS) and polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) in hyperlipidemia patients.Results Among the 180 hyperlipidemia patients of Ningxia Hui population,the frequency of CYP2C9*3 alleles was 3.33% and mutation rate in men(3.05%) was significantly higher than that in women(0.28%)(P0.05).The frequency of MSA2756G(15.83%) alleles was significantly higher than that in healthy control group(10.25%)(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Xi'an Jiaotong University(Medical Sciences)
Year:
2004
Type:
Article
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